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Melanoma

Cause
Symptoms
Diagnosis
Treatment options
Prognosis

What causes Melanoma cancer?

Abnormal-looking moles, called dysplastic nevi or atypical moles may be more likely than normal moles to develop into melanoma.

In some families, many members have a large number of dysplastic nevi, and some have had melanoma. Members of these families have a very high risk for melanoma.

Symptoms

The first sign of melanoma is a change in the size, shape, or color of an existing mole. When melanoma develops in an existing mole, the texture of the mole can change. For example, it can become hard, lumpy, or scaly. Although a melanoma may feel different and may itch, ooze, or bleed, it usually does not cause pain. It is important that melanoma be detected as early as possible. The disease can be cured if it is diagnosed and treated when the tumor is thin and has not deeply invaded the skin. However, if a melanoma is not removed early, cancer cells can grow downward from the skin surface, invading healthy tissue. When a melanoma becomes thick and deep, the disease often spreads to other parts of the body and is difficult to control.

Diagnosis

A biopsy is the only method of making a definite diagnosis. If melanoma is found, the extent, or stage, of the disease should be assessed before planning treatment. The treatment plan takes into account the thickness of the tumor, how deeply the melanoma has invaded the skin, and whether melanoma cells have spread to nearby lymph nodes or other parts of the body. Removal of nearby lymph nodes for examination under a microscope is sometimes necessary. The doctor conducts a thorough physical examination and, depending on the thickness of the tumor, may order chest x-rays, blood tests, and scans of the liver, bones, and brain.

Treatment:

Treatment for melanoma depends on the extent of disease and the patient's age and general health.

Surgery to remove a melanoma is the standard treatment for this disease. It is necessary to remove not only the tumor but also some normal tissue around it to decrease the chance that any cancer cells will be left in the area.

If a large area of tissue is removed, a skin graft may need to be done at the same time.

For melanomas that have spread to other parts of the body, other methods of treatment, such as chemotherapy, biological therapy, radiation therapy, or a combination of these methods are used.

Melanoma patients have an increased risk of developing new melanomas. Some also are at risk for a recurrence of the original melanoma in nearby skin or in other parts of the body.

Prognosis:

Skin cancer has a better prognosis, or outcome, than most other types of cancer. It is generally curable. Even though most skin cancers are cured, people who have been treated for skin cancer have a higher-than-average risk of developing a new cancer of the skin.