Allergies - May sometimes occur with this drug. In older adults - Confusion, restlessness and nervousness, arrhythmias, bradycardia, palpitation and angina pectoris are more likely to occur .Adverse reactions like aplastic anaemia,hepatitis, steven-johnson syndrome have been reported.Pregnancy - There are reports of babies having low birth weight, small head size, skull and facial defects, underdeveloped fingernails, and delays in growth, when their mothers had taken carbamazepine in high doses during pregnancy. Studies in animals have revealed that carbamazepine causes birth defects when given in large doses. Therefore, the use of carbamazepine during pregnancy should be treated with caution. Breast-feeding - Carbamazepine passes into the breast milk, and in some cases the baby may receive sufficient amounts to cause adverse effects. Children - Behavior changes are more likely to occur in children.

Carbamazepine is an enzyme inducer.Its metabolism is induced by phenobarbitone, phenytoin, valproate and vice versa. It has also been found to reduce the blood levels of valproic acid. Erythromycin inhibits the metabolism of carbamazepine. By enzyme induction it reduces the efficacy of oral contraceptives.

Brand Names

Carbadac 200 (Cadila), Carbatol (Torrent), Carbazin (Saga Labs), Carmaz (Natco), Epinil (Themis Pharma), Mazetol (SPPL), Mezapin (LA Pharma), Tegretol (Novartis), Versizur (Micro Labs), Zen Retard (Intas), Zeptol (Sun Pharma)

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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