Cephamandole is more effective against gram negative organisms including Enterobacter, Klebsiella and Proteus and less active against Gram positive organisms than first generation Cephalosporins .

For bacterial infections: Injection dose: Adults: 500 milligrams (mg) to 2 grams every four to eight hours, injected IV or IM.

Contra Indications

Cefamandole is contraindicated in pregnancy, lactation and hypersensitivity to cephalosporins.

Precautions

Precautions are to be taken in Renal disease when the dose of the drug needs to be reduced and when diuretics are used concurrently.

Interactions

Probenecid may increase the blood level of Cefamandole. Concurrent use of diuretic with Cefamandole may increase the nephrotoxicity.

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions

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